The combination of nanoparticles and hydrogels has proven to be an effective way for creating biomaterials with specific functions. It is becoming increasingly easier to create nanocomposite hydrogels that exhibit increased performance across a range of electrical, mechanical, and biological properties thanks to accessible engineering methodologies. Nanocomposite hydrogels were designed to address the shortcomings of hydrogels by integrating various types of nanoparticles or nanostructures into the hydrogel network. For a variety of biomedical applications, the development of multifunctional nanocomposite materials is of tremendous interest. Incorporating functional nanoparticles into hydrogels is a popular method for creating customised Nanocomposites. The use of metal nanoparticles (NPs) in hydrogels has become a new developing study field in tissue engineering and regenerative medicine. Tissue damage and degeneration were common outcomes of disease, injury, and trauma. The treatment usually involves the transplantation of tissue from the same patient or another individual for repair, replacement, or regeneration. The objective of the study to know the nanoparticle-hydrogel composites are currently used in biomedical applications.